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Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity

Advances in regenerative medicine have led to the construction of many types of organoids, which reproduce important aspects of endogenous organs but may be limited or disorganized in nature. While their usefulness for restoring function remains unclear, they have undoubted usefulness in research, d...

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Detalles Bibliográficos
Autores principales: Lawrence, M.L., Elhendawi, M., Morlock, M., Liu, W., Liu, S., Palakkan, A., Seidl, L.F., Hohenstein, P., Sjögren, A.K., Davies, J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861638/
https://www.ncbi.nlm.nih.gov/pubmed/35243244
http://dx.doi.org/10.1016/j.isci.2022.103884