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Microtubule assembly and disassembly dynamics model: Exploring dynamic instability and identifying features of Microtubules’ Growth, Catastrophe, Shortening, and Rescue

Microtubules (MTs), a cellular structure element, exhibit dynamic instability and can switch stochastically from growth to shortening; but the factors that trigger these processes at the molecular level are not understood. We developed a 3D Microtubule Assembly and Disassembly DYnamics (MADDY) model...

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Detalles Bibliográficos
Autores principales: Kliuchnikov, Evgenii, Klyshko, Eugene, Kelly, Maria S., Zhmurov, Artem, Dima, Ruxandra I., Marx, Kenneth A., Barsegov, Valeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861655/
https://www.ncbi.nlm.nih.gov/pubmed/35242287
http://dx.doi.org/10.1016/j.csbj.2022.01.028