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A group B Streptococcus alpha-like protein subunit vaccine induces functionally active antibodies in humans targeting homotypic and heterotypic strains

Maternal vaccination is a promising strategy for preventing neonatal disease caused by group B Streptococcus. The safety and immunogenicity of the prototype vaccine GBS-NN, a fusion protein consisting of the N-terminal domains of the alpha-like proteins (Alp) αC and Rib, were recently evaluated favo...

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Detalles Bibliográficos
Autores principales: Pawlowski, Andrzej, Lannergård, Jonas, Gonzalez-Miro, Majela, Cao, Duojia, Larsson, Sara, Persson, Jenny J., Kitson, Geoff, Darsley, Michael, Rom, Ane Lilleøre, Hedegaard, Morten, Fischer, Per B., Johansson-Lindbom, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861819/
https://www.ncbi.nlm.nih.gov/pubmed/35243418
http://dx.doi.org/10.1016/j.xcrm.2022.100511