Endothelial Cells Promote Productive HIV Infection of Resting CD4(+) T Cells by an Integrin-Mediated Cell Adhesion-Dependent Mechanism

Resting CD4(+) T cells are primary targets of early HIV infection events in vivo, but do not readily support HIV replication in vitro. This barrier to infection can be overcome by exposing resting CD4(+) T cells to endothelial cells (ECs). ECs line blood vessels and direct T cell trafficking into in...

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Detalles Bibliográficos
Autores principales: Card, Catherine M., Abrenica, Bernard, McKinnon, Lyle R., Ball, Terry Blake, Su, Ruey-Chyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861939/
https://www.ncbi.nlm.nih.gov/pubmed/34465136
http://dx.doi.org/10.1089/aid.2021.0034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861939/
https://www.ncbi.nlm.nih.gov/pubmed/34465136
http://dx.doi.org/10.1089/aid.2021.0034

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