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Endothelial Cells Promote Productive HIV Infection of Resting CD4(+) T Cells by an Integrin-Mediated Cell Adhesion-Dependent Mechanism
Resting CD4(+) T cells are primary targets of early HIV infection events in vivo, but do not readily support HIV replication in vitro. This barrier to infection can be overcome by exposing resting CD4(+) T cells to endothelial cells (ECs). ECs line blood vessels and direct T cell trafficking into in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861939/ https://www.ncbi.nlm.nih.gov/pubmed/34465136 http://dx.doi.org/10.1089/aid.2021.0034 |