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Non‐Obese MKR Mouse Model of Type 2 Diabetes Reveals Skeletal Alterations in Mineralization and Material Properties

Obesity is a common comorbidity of type 2 diabetes (T2D). Therefore, increased risk of fragility fractures in T2D is often confounded by the effects of obesity. This study was conducted to elucidate the mechanistic basis by which T2D alone leads to skeletal fragility. We hypothesized that obesity in...

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Detalles Bibliográficos
Autores principales: Tice, Matthew J.L., Bailey, Stacyann, Sroga, Grażyna E., Gallagher, Emily J., Vashishth, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861985/
https://www.ncbi.nlm.nih.gov/pubmed/35229063
http://dx.doi.org/10.1002/jbm4.10583