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Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

OBJECTIVE: In this study, we determined whether Helicobacter pylori (H. pylori) infection dampens the efficacy of cancer immunotherapies. DESIGN: Using mouse models, we evaluated whether immune checkpoint inhibitors or vaccine-based immunotherapies are effective in reducing tumour volumes of H. pylo...

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Detalles Bibliográficos
Autores principales: Oster, Paul, Vaillant, Laurie, Riva, Erika, McMillan, Brynn, Begka, Christina, Truntzer, Caroline, Richard, Corentin, Leblond, Marine M, Messaoudene, Meriem, Machremi, Elisavet, Limagne, Emeric, Ghiringhelli, Francois, Routy, Bertrand, Verdeil, Gregory, Velin, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862014/
https://www.ncbi.nlm.nih.gov/pubmed/34253574
http://dx.doi.org/10.1136/gutjnl-2020-323392