Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma

OBJECTIVE: Infection by HBV is the main risk factor for hepatocellular carcinoma (HCC) worldwide. HBV directly drives carcinogenesis through integrations in the human genome. This study aimed to precisely characterise HBV integrations, in relation with viral and host genomics and clinical features....

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Detalles Bibliográficos
Autores principales: Péneau, Camille, Imbeaud, Sandrine, La Bella, Tiziana, Hirsch, Theo Z, Caruso, Stefano, Calderaro, Julien, Paradis, Valerie, Blanc, Jean-Frederic, Letouzé, Eric, Nault, Jean-Charles, Amaddeo, Giuliana, Zucman-Rossi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862055/
https://www.ncbi.nlm.nih.gov/pubmed/33563643
http://dx.doi.org/10.1136/gutjnl-2020-323153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862055/
https://www.ncbi.nlm.nih.gov/pubmed/33563643
http://dx.doi.org/10.1136/gutjnl-2020-323153

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