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Novel pathomechanism for spontaneous bacterial peritonitis: disruption of cell junctions by cellular and bacterial proteases

OBJECTIVE: Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of liver cirrhosis with a 1-year mortality of 66%. Bacterial translocation (BT) from the intestine to the mesenteric lymph nodes is crucial for the pathogenesis of SBP. DESIGN: Since BT presupposes a leaky intestin...

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Detalles Bibliográficos
Autores principales: Haderer, Marika, Neubert, Philip, Rinner, Eva, Scholtis, Annika, Broncy, Lucile, Gschwendtner, Heidi, Kandulski, Arne, Pavel, Vlad, Mehrl, Alexander, Brochhausen, Christoph, Schlosser, Sophie, Gülow, Karsten, Kunst, Claudia, Müller, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862089/
https://www.ncbi.nlm.nih.gov/pubmed/33707230
http://dx.doi.org/10.1136/gutjnl-2020-321663