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HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4

OBJECTIVE: HCV-genotype 4 infections are a major cause of liver diseases in the Middle East/Africa with certain subtypes associated with increased risk of direct-acting antiviral (DAA) treatment failures. We aimed at developing infectious genotype 4 cell culture systems to understand the evolutionar...

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Detalles Bibliográficos
Autores principales: Pham, Long V., Pedersen, Martin Schou, Fahnøe, Ulrik, Fernandez-Antunez, Carlota, Humes, Daryl, Schønning, Kristian, Ramirez, Santseharay, Bukh, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862099/
https://www.ncbi.nlm.nih.gov/pubmed/33833066
http://dx.doi.org/10.1136/gutjnl-2020-323585