Ginkgobiloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways

BACKGROUND: Our previous study indicated that Ginkgo biloba leaf extract (EGb) could protect against cisplatin-induced acute kidney injury in rabbits. The present study aimed to determine the effects and potential molecular mechanisms of EGb on chronic renal interstitial fibrosis induced by cisplati...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Congying, Zhang, Yansong, Zhong, Xiaobin, Lu, Sisi, Zou, Xiaoqin, Yang, Yufang, Huang, Songqing, Huang, Zhenguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862328/
https://www.ncbi.nlm.nih.gov/pubmed/35189929
http://dx.doi.org/10.1186/s13020-022-00574-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862328/
https://www.ncbi.nlm.nih.gov/pubmed/35189929
http://dx.doi.org/10.1186/s13020-022-00574-y

Ejemplares similares