Ginkgobiloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways

BACKGROUND: Our previous study indicated that Ginkgo biloba leaf extract (EGb) could protect against cisplatin-induced acute kidney injury in rabbits. The present study aimed to determine the effects and potential molecular mechanisms of EGb on chronic renal interstitial fibrosis induced by cisplati...

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Detalles Bibliográficos
Autores principales: Wei, Congying, Zhang, Yansong, Zhong, Xiaobin, Lu, Sisi, Zou, Xiaoqin, Yang, Yufang, Huang, Songqing, Huang, Zhenguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862328/
https://www.ncbi.nlm.nih.gov/pubmed/35189929
http://dx.doi.org/10.1186/s13020-022-00574-y

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