Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization

BACKGROUND: Glioblastoma (GB) is the most common and highly malignant brain tumor characterized by aggressive growth and resistance to alkylating chemotherapy. Autophagy induction is one of the hallmark effects of anti-GB therapies with temozolomide (TMZ). However, the non-classical form of autophag...

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Detalles Bibliográficos
Autores principales: Li, Zhuang, Fu, Wen-Juan, Chen, Xiao-Qing, Wang, Shuai, Deng, Ru-Song, Tang, Xiao-Peng, Yang, Kai-Di, Niu, Qin, Zhou, Hong, Li, Qing-Rui, Lin, Yong, Liang, Mei, Li, Si-Si, Ping, Yi-Fang, Liu, Xin-Dong, Bian, Xiu-Wu, Yao, Xiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862393/
https://www.ncbi.nlm.nih.gov/pubmed/35193644
http://dx.doi.org/10.1186/s13046-022-02291-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862393/
https://www.ncbi.nlm.nih.gov/pubmed/35193644
http://dx.doi.org/10.1186/s13046-022-02291-8

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