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Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia

OBJECTIVE: Parkinson disease (PD) is defined by the accumulation of misfolded α‐synuclein (α‐syn) in Lewy bodies and Lewy neurites. It affects multiple cortical and subcortical neuronal populations. The majority of people with PD develop dementia, which is associated with Lewy bodies in neocortex an...

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Detalles Bibliográficos
Autores principales: Miller, Rebecca L., Dhavale, Dhruva D., O’Shea, Jennifer Y., Andruska, Kristin M., Liu, Jialu, Franklin, Erin E., Buddhala, Chandana, Loftin, Susan K., Cirrito, John R., Perrin, Richard J., Cairns, Nigel J., Campbell, Meghan C., Perlmutter, Joel S., Kotzbauer, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862415/
https://www.ncbi.nlm.nih.gov/pubmed/35060360
http://dx.doi.org/10.1002/acn3.51482