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Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia
OBJECTIVE: Parkinson disease (PD) is defined by the accumulation of misfolded α‐synuclein (α‐syn) in Lewy bodies and Lewy neurites. It affects multiple cortical and subcortical neuronal populations. The majority of people with PD develop dementia, which is associated with Lewy bodies in neocortex an...
Autores principales: | Miller, Rebecca L., Dhavale, Dhruva D., O’Shea, Jennifer Y., Andruska, Kristin M., Liu, Jialu, Franklin, Erin E., Buddhala, Chandana, Loftin, Susan K., Cirrito, John R., Perrin, Richard J., Cairns, Nigel J., Campbell, Meghan C., Perlmutter, Joel S., Kotzbauer, Paul T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862415/ https://www.ncbi.nlm.nih.gov/pubmed/35060360 http://dx.doi.org/10.1002/acn3.51482 |
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