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Modeling the stimulation by glutathione of the steady state kinetics of an adenosine triphosphate binding cassette transporter

We report the steady state ATPase activities of the ATP Binding Cassette (ABC) exporter NaAtm1 in the absence and presence of a transported substrate, oxidized glutathione (GSSG), in detergent, nanodiscs, and proteoliposomes. The steady state kinetic data were fit to the “nonessential activator mode...

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Detalles Bibliográficos
Autores principales: Fan, Chengcheng, Rees, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862428/
https://www.ncbi.nlm.nih.gov/pubmed/34878193
http://dx.doi.org/10.1002/pro.4250