Activation of dopamine receptor D1 promotes osteogenic differentiation and reduces glucocorticoid-induced bone loss by upregulating the ERK1/2 signaling pathway

BACKGROUND: The inhibition of osteogenic differentiation is a major factor in glucocorticoid-induced bone loss, but there is currently no effective treatment. Dopamine, a major neurotransmitter, transmits signals via five different seven-transmembrane G protein-coupled receptors termed D1 to D5. Alt...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Feng, Chengcheng, Zhang, Weicheng, Wang, Zhidong, Zhong, Mengdan, Tang, Wenkai, Wang, Zhifang, Shi, Haiwei, Yin, Zhengyu, Shi, Jiandong, Huang, Yu, Xiao, Long, Geng, Dechun, Wang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862482/
https://www.ncbi.nlm.nih.gov/pubmed/35189819
http://dx.doi.org/10.1186/s10020-022-00453-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862482/
https://www.ncbi.nlm.nih.gov/pubmed/35189819
http://dx.doi.org/10.1186/s10020-022-00453-0

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