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A fluorometric assay to determine the protective effect of glucose-6-phosphate dehydrogenase (G6PD) against a Plasmodium spp. infection in females heterozygous for the G6PD gene: proof of concept in Plasmodium falciparum

OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency offers some protection against malaria; however, the degree of protection is poorly described and likely to vary with G6PD genotype and Plasmodium species. We present a novel approach to quantify the differential invasion rates of P. fal...

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Detalles Bibliográficos
Autores principales: Rumaseb, Angela, Marfurt, Jutta, Kho, Steven, Kahn, Maria, Price, Ric N., Ley, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862483/
https://www.ncbi.nlm.nih.gov/pubmed/35193663
http://dx.doi.org/10.1186/s13104-022-05952-1