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miR-223-3p carried by cancer-associated fibroblast microvesicles targets SORBS1 to modulate the progression of gastric cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) aggravate gastric cancer (GC) development. METHODS: Combined with bioinformatics analysis and literature review, miR-223-3p had high expression in microvesicles (MVs) derived from GC CAFs, and it could modulate SORBS1. miR-223-3p and SORBS1 mRNA level...

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Detalles Bibliográficos
Autores principales: Jin, Xiaoli, Qiu, Xi, Huang, Yi, Zhang, Hang, Chen, Kaibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862537/
https://www.ncbi.nlm.nih.gov/pubmed/35193596
http://dx.doi.org/10.1186/s12935-022-02513-1