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Is the mitochondrion a promising drug target in trypanosomatids?

The trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are etiological agents of important neglected tropical diseases, affecting millions of people worldwide, and the drugs available for these diseases present several limitations. Novel efficient and nontoxic drugs are necess...

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Detalles Bibliográficos
Autores principales: Pedra-Rezende, Yasmin, Bombaça, Ana Cristina Souza, Menna-Barreto, Rubem Figueiredo Sadok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862782/
https://www.ncbi.nlm.nih.gov/pubmed/35195164
http://dx.doi.org/10.1590/0074-02760210379