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Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against native-like vaccine and delta variant spike trimers

Traditional cellular and live-virus methods for detection of SARS-CoV-2 neutralizing antibodies (nAbs) are labor- and time-intensive, and thus not suited for routine use in the clinical lab to predict vaccine efficacy and natural immune protection. Here, we report the development and validation of a...

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Detalles Bibliográficos
Autores principales: Cheedarla, Narayanaiah, Verkerke, Hans P., Potlapalli, Sindhu, McLendon, Kaleb Benjamin, Patel, Anamika, Frank, Filipp, Damhorst, Gregory L., Wu, Huixia, O’Sick, William Henry, Graciaa, Daniel, Hudaib, Fuad, Alter, David N, Bryksin, Jeannette, Ortlund, Eric A., Guarner, Jeanette, Auld, Sara, Shah, Sarita, Lam, Wilbur, Mattoon, Dawn, Johnson, Joseph M, Wilson, David H, Dhodapkar, Madhav V., Stowell, Sean R., Neish, Andrew S., Roback, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863158/
https://www.ncbi.nlm.nih.gov/pubmed/35194599
http://dx.doi.org/10.21203/rs.3.rs-1322411/v1