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Efficacy of ChAdOx1 vaccines against SARS-CoV-2 Variants of Concern Beta, Delta and Omicron in the Syrian hamster model

ChAdOx1 nCoV-19 (AZD1222) is a replication-deficient simian adenovirus–vectored vaccine encoding the spike (S) protein of SARS-CoV-2, based on the first published full-length sequence (Wuhan-1). AZD1222 was shown to have 74% vaccine efficacy (VE) against symptomatic disease in clinical trials and ov...

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Detalles Bibliográficos
Autores principales: van Doremalen, Neeltje, Schulz, Jonathan E., Adney, Danielle R., Saturday, Taylor A., Fischer, Robert J., Yinda, Claude Kwe, Thakur, Nazia, Newman, Joseph, Ulaszewska, Marta, Belij-Rammerstorfer, Sandra, Saturday, Greg, Spencer, Alexandra J., Bailey, Dalan, Gilbert, Sarah C., Lambe, Teresa, Munster, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863164/
https://www.ncbi.nlm.nih.gov/pubmed/35194602
http://dx.doi.org/10.21203/rs.3.rs-1343927/v1