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PHF10 subunit of PBAF complex mediates transcriptional activation by MYC

The PBAF complex, a member of SWI/SNF family of chromatin remodelers, plays an essential role in transcriptional regulation. We revealed a disease progression associated elevation of PHF10 subunit of PBAF in clinical melanoma samples. In melanoma cell lines, PHF10 interacts with MYC and facilitates...

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Detalles Bibliográficos
Autores principales: Soshnikova, N.V., Tatarskiy, E.V., Tatarskiy, V.V., Klimenko, N.S., Shtil, A. A., Nikiforov, M.A., Georgieva, S.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863208/
https://www.ncbi.nlm.nih.gov/pubmed/34465901
http://dx.doi.org/10.1038/s41388-021-01994-0