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A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans

Cell invasion is an initiating event during tumor cell metastasis and an essential process during development. A screen of C. elegans orthologs of genes overexpressed in invasive human melanoma cells has identified several components of the conserved DNA pre-replication complex (pre-RC) as positive...

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Detalles Bibliográficos
Autores principales: Lattmann, Evelyn, Deng, Ting, Walser, Michael, Widmer, Patrizia, Rexha-Lambert, Charlotte, Prasad, Vibhu, Eichhoff, Ossia, Daube, Michael, Dummer, Reinhard, Levesque, Mitchell P., Hajnal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863262/
https://www.ncbi.nlm.nih.gov/pubmed/35192608
http://dx.doi.org/10.1371/journal.pbio.3001317