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SARS-CoV-2 spike antigen quantification by targeted mass spectrometry of a virus-based vaccine

The spike glycoprotein mediates virus binding to the host cells and is a key target for vaccines development. One SARS-CoV-2 vaccine is based on vesicular stomatitis virus (VSV), in which the native surface glycoprotein has been replaced by the SARS-CoV-2 spike protein (VSV-ΔG-spike). The titer of t...

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Detalles Bibliográficos
Autores principales: Rosen, Osnat, Jayson, Avital, Dor, Eyal, Epstein, Eyal, Makovitzki, Arik, Cherry, Lilach, Lupu, Edith, Monash, Arik, Borni, Sarah, Baruchi, Tzadok, Laskar, Orly, Shmaya, Shlomo, Rosenfeld, Ronit, Levy, Yinon, Schuster, Ofir, Feldberg, Liron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863330/
https://www.ncbi.nlm.nih.gov/pubmed/35217103
http://dx.doi.org/10.1016/j.jviromet.2022.114498