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Blocking cholesterol storage to treat Alzheimer’s disease

Cholesterol serves as an essential lipid molecule in various membrane organelles of mammalian cells. The metabolites of cholesterol also play important functions. Acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1), also named as sterol O-acyltransferase 1, is a membrane-bound enzyme residing at...

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Detalles Bibliográficos
Autores principales: Chang, Ta Yuan, Chang, Catherine C. Y., Harned, Taylor C., De La Torre, Adrianna L., Lee, Junghoon, Huynh, Thao N., Gow, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863366/
https://www.ncbi.nlm.nih.gov/pubmed/35199105
http://dx.doi.org/10.37349/ent.2021.00014