Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE

RAGE, a druggable inflammatory receptor, is known to function as an oligomer but the exact oligomerization mechanism remains poorly understood. Previously we have shown that heparan sulfate (HS) plays an active role in RAGE oligomerization. To understand the physiological significance of HS-induced...

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Detalles Bibliográficos
Autores principales: Li, Miaomiao, Ong, Chih Yean, Langouët-Astrié, Christophe J, Tan, Lisi, Verma, Ashwni, Yang, Yimu, Zhang, Xiaoxiao, Shah, Dhaval K, Schmidt, Eric P, Xu, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863369/
https://www.ncbi.nlm.nih.gov/pubmed/35137686
http://dx.doi.org/10.7554/eLife.71403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863369/
https://www.ncbi.nlm.nih.gov/pubmed/35137686
http://dx.doi.org/10.7554/eLife.71403

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