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Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection

Nasal mucosal explant (NEs) cultured at an air–liquid interface mimics in vivo conditions more accurately than monolayer cultures of respiratory cell lines or primary cells cultured in flat-bottom microtiter wells. NEs might be relevant for studies of host-pathogen interactions and antiviral immune...

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Detalles Bibliográficos
Autores principales: Starbæk, Sofie M.R., Andersen, Malene Rask, Brogaard, Louise, Spinelli, Anna, Rapson, Victoria, Glud, Helena Aagaard, Larsen, Lars E., Heegaard, Peter M.H., Nauwynck, Hans, Skovgaard, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier GmbH. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863374/
https://www.ncbi.nlm.nih.gov/pubmed/35255458
http://dx.doi.org/10.1016/j.imbio.2022.152192