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Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies

Large-scale insecticide application is a primary weapon in the control of insect pests in agriculture. However, a growing body of evidence indicates that it is contributing to the global decline in population sizes of many beneficial insect species. Spinosad emerged as an organic alternative to synt...

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Detalles Bibliográficos
Autores principales: Martelli, Felipe, Hernandes, Natalia H, Zuo, Zhongyuan, Wang, Julia, Wong, Ching-On, Karagas, Nicholas E, Roessner, Ute, Rupasinghe, Thusita, Robin, Charles, Venkatachalam, Kartik, Perry, Trent, Batterham, Philip, Bellen, Hugo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863376/
https://www.ncbi.nlm.nih.gov/pubmed/35191376
http://dx.doi.org/10.7554/eLife.73812