Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

In continuation of our previous studies to optimise potent carbonic anhydrase inhibitors, two new series of isatin N-phenylacetamide based sulphonamides were synthesised and screened for their human (h) carbonic anhydrase (EC 4.2.1.1) inhibitory activities against four isoforms hCA I, hCA II, hCA IX...

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Detalles Bibliográficos
Autores principales: Said, Mona F., George, Riham F., Petreni, Andrea, Supuran, Claudiu T., Mohamed, Nada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863381/
https://www.ncbi.nlm.nih.gov/pubmed/35168458
http://dx.doi.org/10.1080/14756366.2022.2036137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863381/
https://www.ncbi.nlm.nih.gov/pubmed/35168458
http://dx.doi.org/10.1080/14756366.2022.2036137

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