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Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models

An excess phosphate burden in renal disease has pathological consequences for bone, kidney, and heart. Therapies to decrease intestinal phosphate absorption have been used to address the problem, but with limited success. Here, we describe the in vivo effects of a novel potent inhibitor of the intes...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojun, Xu, Yanping, Yu, Xiaohong, Dey, Asim, Zhang, Hong Y., Zink, Charity M., Wodka, Derek, Porter, Gina, Matter, William F., Porras, Leah, Reidy, Charles A., Peterson, Jeffrey A., Mattioni, Brian E., Haas, Joseph V., Kowala, Mark C., Wetterau, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863579/
https://www.ncbi.nlm.nih.gov/pubmed/35194979
http://dx.doi.org/10.1002/prp2.938