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Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)(2)α2(IV)(1) heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a limited tissue distribution. The absence o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863674/ https://www.ncbi.nlm.nih.gov/pubmed/35223933 http://dx.doi.org/10.3389/fmed.2022.846152 |