Rapamycin attenuated podocyte apoptosis via upregulation of nestin in Ang II-induced podocyte injury

BACKGROUND: Angiotensin II (Ang II) contributes to the progression of glomerulosclerosis, mainly by inducing podocyte injury. Convincing evidence indicates that the mTOR inhibitor rapamycin could play a fundamental role in protection against podocyte injury. Nestin, a major cytoskeletal protein, is...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Huimin, Zhao, Yajie, He, Tiantian, Wen, Xianli, Qu, Gaoting, Li, Shanwen, Gan, Weihua, Zhang, Aiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863685/
https://www.ncbi.nlm.nih.gov/pubmed/35149934
http://dx.doi.org/10.1007/s11033-021-07029-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863685/
https://www.ncbi.nlm.nih.gov/pubmed/35149934
http://dx.doi.org/10.1007/s11033-021-07029-x

Ejemplares similares