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Metal Ions Bound to Prion Protein Affect its Interaction with Plasminogen Activation System

Prion diseases are a group of neurodegenerative diseases, which can progress rapidly. Previous data have demonstrated that prion protein (PrP) stimulates activation of plasminogen (Plg) by tissue plasminogen activator (tPA). In this study, using spectroscopic method, we aimed to determine whether Pr...

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Detalles Bibliográficos
Autores principales: Borumand, Maryam, Ellis, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863686/
https://www.ncbi.nlm.nih.gov/pubmed/35038117
http://dx.doi.org/10.1007/s10930-021-10035-4