Tryptophan 2,3-Dioxygenase-2 in Uterine Leiomyoma: Dysregulation by MED12 Mutation Status

Uterine leiomyomas (fibroids) are common benign tumors in women. The tryptophan metabolism through the kynurenine pathway plays important roles in tumorigenesis in general. Leiomyomas expressing mutated mediator complex subunit 12 (mut-MED12) were reported to contain significantly decreased tryptoph...

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Detalles Bibliográficos
Autores principales: Hutchinson, Anne P., Yin, Ping, Neale, Ilona, Coon, John S., Kujawa, Stacy A., Liu, Shimeng, Bulun, Serdar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Fibroid: Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863695/
https://www.ncbi.nlm.nih.gov/pubmed/35064560
http://dx.doi.org/10.1007/s43032-022-00852-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863695/
https://www.ncbi.nlm.nih.gov/pubmed/35064560
http://dx.doi.org/10.1007/s43032-022-00852-y

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