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Serum-derived miR-574-5p-containing exosomes contribute to liver fibrosis by activating hepatic stellate cells

AIM: To investigate the association of serum exosomes miR-574-5p with liver fibrosis, and explore the effect and mechanism of serum exosomes on HSC activation. MATERIALS AND METHODS: Using serum samples collected from healthy adults and patients with liver cirrhosis, we extracted human serum exosome...

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Detalles Bibliográficos
Autores principales: Zhou, Xia, Liang, Ziyu, Qin, Shanyu, Ruan, Xianxian, Jiang, Haixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863722/
https://www.ncbi.nlm.nih.gov/pubmed/34843038
http://dx.doi.org/10.1007/s11033-021-07008-2