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The deubiquitinase Usp27x as a novel regulator of cFLIP(L) protein expression and sensitizer to death-receptor-induced apoptosis

Death receptors are transmembrane proteins that can induce the activation of caspase-8 upon ligand binding, initiating apoptosis. Recent work has highlighted the great molecular complexity of death receptor signalling, in particular through ubiquitination/deubiquitination. We have earlier defined th...

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Detalles Bibliográficos
Autores principales: Dold, Manuel Nico, Ng, Xiulin, Alber, Claudia, Gentle, Ian Edward, Häcker, Georg, Weber, Arnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863773/
https://www.ncbi.nlm.nih.gov/pubmed/35044632
http://dx.doi.org/10.1007/s10495-021-01706-9