Cargando…
The deubiquitinase Usp27x as a novel regulator of cFLIP(L) protein expression and sensitizer to death-receptor-induced apoptosis
Death receptors are transmembrane proteins that can induce the activation of caspase-8 upon ligand binding, initiating apoptosis. Recent work has highlighted the great molecular complexity of death receptor signalling, in particular through ubiquitination/deubiquitination. We have earlier defined th...
Autores principales: | Dold, Manuel Nico, Ng, Xiulin, Alber, Claudia, Gentle, Ian Edward, Häcker, Georg, Weber, Arnim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863773/ https://www.ncbi.nlm.nih.gov/pubmed/35044632 http://dx.doi.org/10.1007/s10495-021-01706-9 |
Ejemplares similares
-
FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP
por: Tsuchiya, Yuichi, et al.
Publicado: (2015) -
Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP
por: Hirpara, Jayshree L., et al.
Publicado: (2019) -
cFLIP expression is altered in severe corticosteroid-resistant asthma
por: Lazarev, Dennis, et al.
Publicado: (2014) -
cFLIP overexpression in T cells in thymoma-associated myasthenia gravis
por: Belharazem, Djeda, et al.
Publicado: (2015) -
Computational modelling of LY303511 and TRAIL-induced apoptosis suggests
dynamic regulation of cFLIP
por: Shi, Yuan, et al.
Publicado: (2013)