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Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model

Uterine leiomyosarcoma (LMS) contributes to a significant proportion of uterine cancer deaths. It is a rare and high-risk gynecological cancer. LMS is challenging to the treatment due to the resistance of several therapies. The activation of the Hedgehog (HH) pathway has been reported in several typ...

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Detalles Bibliográficos
Autores principales: Garcia, Natalia, Ulin, Mara, Ali, Mohamed, Al-Hendy, Ayman, Carvalho, Katia Candido, Yang, Qiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863774/
https://www.ncbi.nlm.nih.gov/pubmed/34642915
http://dx.doi.org/10.1007/s43032-021-00731-y