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Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model
Uterine leiomyosarcoma (LMS) contributes to a significant proportion of uterine cancer deaths. It is a rare and high-risk gynecological cancer. LMS is challenging to the treatment due to the resistance of several therapies. The activation of the Hedgehog (HH) pathway has been reported in several typ...
Autores principales: | Garcia, Natalia, Ulin, Mara, Ali, Mohamed, Al-Hendy, Ayman, Carvalho, Katia Candido, Yang, Qiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863774/ https://www.ncbi.nlm.nih.gov/pubmed/34642915 http://dx.doi.org/10.1007/s43032-021-00731-y |
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