CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function

Human CYP2B6 enzyme although constitutes relatively low proportion (1–4%) of hepatic cytochrome P450 content, it is the major catalyst of metabolism of several clinically important drugs (efavirenz, cyclophosphamide, bupropion, methadone). High interindividual variability in CYP2B6 function, contrib...

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Detalles Bibliográficos
Autores principales: Mangó, Katalin, Kiss, Ádám Ferenc, Fekete, Ferenc, Erdős, Réka, Monostory, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863776/
https://www.ncbi.nlm.nih.gov/pubmed/35194103
http://dx.doi.org/10.1038/s41598-022-07022-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863776/
https://www.ncbi.nlm.nih.gov/pubmed/35194103
http://dx.doi.org/10.1038/s41598-022-07022-9

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