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CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function
Human CYP2B6 enzyme although constitutes relatively low proportion (1–4%) of hepatic cytochrome P450 content, it is the major catalyst of metabolism of several clinically important drugs (efavirenz, cyclophosphamide, bupropion, methadone). High interindividual variability in CYP2B6 function, contrib...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863776/ https://www.ncbi.nlm.nih.gov/pubmed/35194103 http://dx.doi.org/10.1038/s41598-022-07022-9 |