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Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse

To better understand the molecular mechanisms of tendon healing, we investigated the Murphy Roth’s Large (MRL) mouse, which is considered a model of mammalian tissue regeneration. We show that compared to C57Bl/6J (C57) mice, injured MRL tendons have reduced fibrotic adhesions and cellular prolifera...

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Detalles Bibliográficos
Autores principales: Kallenbach, Jacob G., Freeberg, Margaret A. T., Abplanalp, David, Alenchery, Rahul G., Ajalik, Raquel E., Muscat, Samantha, Myers, Jacquelyn A., Ashton, John M., Loiselle, Alayna, Buckley, Mark R., van Wijnen, Andre J., Awad, Hani A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863792/
https://www.ncbi.nlm.nih.gov/pubmed/35194136
http://dx.doi.org/10.1038/s41598-022-07124-4