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Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse
To better understand the molecular mechanisms of tendon healing, we investigated the Murphy Roth’s Large (MRL) mouse, which is considered a model of mammalian tissue regeneration. We show that compared to C57Bl/6J (C57) mice, injured MRL tendons have reduced fibrotic adhesions and cellular prolifera...
Autores principales: | Kallenbach, Jacob G., Freeberg, Margaret A. T., Abplanalp, David, Alenchery, Rahul G., Ajalik, Raquel E., Muscat, Samantha, Myers, Jacquelyn A., Ashton, John M., Loiselle, Alayna, Buckley, Mark R., van Wijnen, Andre J., Awad, Hani A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863792/ https://www.ncbi.nlm.nih.gov/pubmed/35194136 http://dx.doi.org/10.1038/s41598-022-07124-4 |
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