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Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer’s disease

Short-term memory deficits have been associated with prefrontal cortex (PFC) dysfunction in Alzheimer’s disease (AD) and AD mouse models. Extratelencephalic projection (ET) neurons in the PFC play a key role in short-term working memory, but the mechanism between ET neuronal dysfunction in the PFC a...

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Detalles Bibliográficos
Autores principales: Sun, Qingtao, Zhang, Jianping, Li, Anan, Yao, Mei, Liu, Guangcai, Chen, Siqi, Luo, Yue, Wang, Zhi, Gong, Hui, Li, Xiangning, Luo, Qingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863829/
https://www.ncbi.nlm.nih.gov/pubmed/35194025
http://dx.doi.org/10.1038/s41467-022-28493-4