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ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease – Study Protocol and Baseline Characteristics

BACKGROUND: Detailed characterization of early pathophysiological changes in preclinical Alzheimer's disease (AD) is necessary to enable development of correctly targeted and timed disease-modifying treatments. ASIC-E4 study (“Beta-Amyloid, Synaptic loss, Inflammation and Cognition in healthy A...

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Detalles Bibliográficos
Autores principales: Snellman, Anniina, Ekblad, Laura L., Koivumäki, Mikko, Lindgrén, Noora, Tuisku, Jouni, Perälä, Merja, Kallio, Lila, Lehtonen, Riina, Saunavaara, Virva, Saunavaara, Jani, Oikonen, Vesa, Aarnio, Richard, Löyttyniemi, Eliisa, Parkkola, Riitta, Karrasch, Mira, Zetterberg, Henrik, Blennow, Kaj, Rinne, Juha O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863967/
https://www.ncbi.nlm.nih.gov/pubmed/35222254
http://dx.doi.org/10.3389/fneur.2022.826423