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Evolution of Guanylate Binding Protein (GBP) Genes in Muroid Rodents (Muridae and Cricetidae) Reveals an Outstanding Pattern of Gain and Loss

Guanylate binding proteins (GBPs) are paramount in the host immunity by providing defense against invading pathogens. Multigene families related to the immune system usually show that the duplicated genes can either undergo deletion, gain new functions, or become non-functional. Here, we show that i...

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Detalles Bibliográficos
Autores principales: Côrte-Real, João Vasco, Baldauf, Hanna-Mari, Melo-Ferreira, José, Abrantes, Joana, Esteves, Pedro José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863968/
https://www.ncbi.nlm.nih.gov/pubmed/35222365
http://dx.doi.org/10.3389/fimmu.2022.752186