Cargando…
Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4
RNA interference is required for post-transcriptional silencing, but also has additional roles in transcriptional silencing of centromeres and genome stability. However, these roles have been controversial in mammals. Strikingly, we found that Dicer-deficient embryonic stem cells have strong prolife...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863982/ https://www.ncbi.nlm.nih.gov/pubmed/35194019 http://dx.doi.org/10.1038/s41467-022-28554-8 |