Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core

The molecular events that permit the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to bind and enter cells are important to understand for both fundamental and therapeutic reasons. Spike proteins consist of S1 and S2 domains, which recognize angiotensin-convertin...

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Detalles Bibliográficos
Autores principales: Pak, Alexander J., Yu, Alvin, Ke, Zunlong, Briggs, John A. G., Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863989/
https://www.ncbi.nlm.nih.gov/pubmed/35194049
http://dx.doi.org/10.1038/s41467-022-28654-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863989/
https://www.ncbi.nlm.nih.gov/pubmed/35194049
http://dx.doi.org/10.1038/s41467-022-28654-5

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