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Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core
The molecular events that permit the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to bind and enter cells are important to understand for both fundamental and therapeutic reasons. Spike proteins consist of S1 and S2 domains, which recognize angiotensin-convertin...
Autores principales: | Pak, Alexander J., Yu, Alvin, Ke, Zunlong, Briggs, John A. G., Voth, Gregory A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863989/ https://www.ncbi.nlm.nih.gov/pubmed/35194049 http://dx.doi.org/10.1038/s41467-022-28654-5 |
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